Biomedical sciences publications
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Potential Reporting Bias in fMRI Studies of the Brain
Functional magnetic resonance imaging (fMRI) studies have reported multiple activation foci associated with a variety of conditions, stimuli or tasks.
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Carbon-14 Labeling of K777
The antitrypanosomal agent K777•HCl was labeled with carbon-14 to support absorption, distribution, metabolism, and excretion studies of this potential new drug for the treatment of Chagas disease.
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First Measurement of the BO B2Σ+ Radiative Lifetime by Laser-Induced Fluorescence Via the B2Σ+–X2Σ+ Transition
Observation of the temporal evolution of the fluorescence following laser excitation of boron monoxide molecules to the B 2Σ+ state is used to extract the radiative lifetime and collisional removal rate constant with…
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Longitudinal Analysis of the Electroencephalogram and Sleep Phenotype in the R6/2 Mouse Model of Huntington’s Disease
We conducted a longitudinal characterization of sleep/wake and electroencephalographic activity in the R6/2 mouse model of Huntington’s disease to determine whether analogous electroencephalographic ‘signatures’ could be identified early in disease…
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Curcumin Regulates Colon Cancer by Inhibiting P-Glycoprotein in Cancerous Colon Perfusion Rat Model
In the present study curcumin inhibitory action on p-glycoprotein increased permeability of irinotecan, so in the colon cancer it would be beneficial if curcumin used as add on therapy.
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Comparison of a New Cobinamide-Based Method to a Standard Laboratory Method for Measuring Cyanide in Human Blood
The authors developed and validated a method to quantify cyanide based on the high binding affinity of the vitamin B12 analog, cobinamide, for cyanide and a major spectral change observed…
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Non-Clinical Safety Evaluation of Xoma 3AB, a Novel Triple Antibody Drug Product Targeting Botulinum Toxin Type a, in Sprague-Dawley Rats
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Beta-Carotene Biosynthesis in Probiotic Bacteria
To increase vitamin A coverage in malnourished children, we propose to engineer a probiotic bacterium that will produce β-carotene in the intestine, which will be metabolized to vitamin A.
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Relationship between Cardiovascular Resting State and Visual Attention
We investigated the relationship between blood pressure, resting heart rate and heart rate variability (HRV) and performance in a visuospatial attention task comparing normotensive and hypotensive young adults.
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Evoked Responses During Sleep in Young Heavy Drinkers
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Decision-Making and Brain Structural Substrates in Alcoholism, Hiv Infection, and Their Comorbidity
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Acute Ethanol Reduces Reversal Cost in Discrimination Learning by Reducing Perseverance in Adolescent Rhesus Macaques
The cognitive impact of acute alcohol exposure includes deficits in discrimination and reversal learning, but traditional experimental approaches make it difficult to distinguish the effect of alcohol on discrimination learning…