Biomedical sciences publications

The current study was designed to evaluate the hypnotic and cataplexy-inducing efficacy of a Hcrt antagonist in an animal model with low Hcrt tone and compare the ALM efficacy profile…

In order to learn from prior work we have collated information on molecules screened versus Mtb and their targets which has been made available in the Collaborative Drug Discovery (CDD) database.

Here, the library was utilized to map the global proteolytic specificities of plasma samples obtained from patients with the nephrotic syndrome, known as focal segmental glomerulosclerosis (FSGS).

To increase vitamin A coverage in malnourished children, we propose to engineer a probiotic bacterium that will produce β-carotene in the intestine, which will be metabolized to vitamin A.

This study bridges a carbohydrate microarray discovery and a large-scale serological validation of anti-oligomannose antibodies as novel serum biomarkers of aggressive prostate cancer.

This study investigates whether nicotine may exert its beneficial effects by modulating pre-synaptic dopaminergic function.

We tested sex-smoking interaction in association with lung cancer risk within a population-based case-control study, the Environment and Genetics in Lung Cancer Etiology (EAGLE) Study (Lombardy, Italy, 2002–2005).

The aim of present study was to evaluate the expression of IL17A and occurrence of the IL17A (rs2275913), IL17F (rs763780) and IL23R (rs11209026) gene polymorphisms in different clinical forms or…

There are sex-related differences in circadian rhythms with women having shorter intrinsic periods and earlier phase of both temperature and melatonin rhythms relative to men.

There are sex differences in sleep behavior with women reporting more sleep problems and a poorer sleep quality than men across a wide age range.