Biomedical sciences publications
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Double Dissociation Between Action-Driven and Perception-Driven Conflict Resolution Invoking Anterior Versus Posterior Brain Systems
We manipulated perceptual information that either matched or did not match the relevant color feature of an upcoming Stroop stimulus and recorded hemodynamic brain responses to these events.
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In Vivo Glutamate Decline Associated with Kainic Acid-Induced Status Epilepticus
Here, we present data using in vivo magnetic resonance spectroscopy (MRS) optimized for the detection of glutamate to identify changes that evolve following kainic acid (KA)-induced status epilepticus.
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Bright Lights, Clearly Visible in the Healthcare R&D Tunnel, Could Burn Out for Lack of Funds
The promise of continued healthcare innovation is increasingly threatened by inadequate funding of R&D at many levels: in academic and nonprofit organizations, in small business ventures, and even in large…
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Geo-Based Aerial Surveillance Video Processing for Scene Understanding and Object Tracking
This paper presents an approach to extract semantic layers from aerial surveillance videos for scene understanding and object tracking.
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Alcohol Consumption and Lung Cancer Risk in the Environment and Genetics in Lung Cancer Etiology (Eagle) Study
The authors investigated the relation between alcohol consumption and lung cancer risk in the Environment and Genetics in Lung Cancer Etiology (EAGLE) Study, a population-based case-control study.
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Effect of Aedes Aegypti Saliva on Macrophage Cytokine Expression and on Dengue Infection
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Alpha-Synuclein-Glucocerebrosidase Interactions in Pharmacological Gaucher Models: a Biological Link Between Gaucher Disease and Parkinsonism
The aim of this study was to determine whether there is a relationship between alpha-synuclein (α-syn), a key protein in Parkinson's disease pathogenesis, and abnormalities in glucocerebroside (GC) catabolism that…
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A Genome-Wide Association Study of Lung Cancer Identifies a Region of Chromosome 5P15 Associated with Risk for Adenocarcinoma
We conducted a GWAS of lung cancer and its major histologic types, genotyping 515,922 single-nucleotide polymorphisms (SNPs) in 5739 lung cancer cases and 5848 controls from one population-based case-control study…
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A Phase I Study of the Nitroimidazole Hypoxia Marker SR4554 Using 19 F Magnetic Resonance Spectroscopy
In this study we investigated higher doses of SR4554 and intratumoral localisation of the 19F MRS signal.
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Impact of Alcoholism on Sleep Architecture and EEG Power Spectra in Men and Women
We aimed to determine the impact of alcoholism on sleep architecture and sleep EEG power spectra in men and women with uncomplicated alcoholism.
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Parallel Interhemispheric Processing in Hemineglect: Relation to Visual Field Defects
To study whether unconscious parallel processing depends on visual functional integrity, we compared the performance of neglect patients with visual field defects (VFDs) (n = 11) and hemianopic patients with partial or complete blindness…
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Biodistribution, Toxicity and Radiation Dosimetry Studies of the Serotonin Transporter Radioligand 4-[18F]-ADAM in Rats and Monkeys
4-[18F]-ADAM is a potent serotonin transport imaging agent. We studied its toxicity in rats and radiation dosimetry in monkeys before human studies are undertaken.