Biomedical sciences publications
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Genome-Wide and Candidate Gene Association Study of Cigarette Smoking Behaviors
The contribution of common genetic variation to one or more established smoking behaviors was investigated in a joint analysis of two genome wide association studies.
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A Consensus Definition of Cataplexy in Mouse Models of Narcolepsy
To establish a common language, the International Working Group on Rodent Models of Narcolepsy reviewed the literature on cataplexy in people with narcolepsy and in dog and mouse models of…
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Interference Between Modalities as a Measure of Processing Inefficiency in Alcoholics
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Multiple Distinct Risk Loci for Nicotine Dependence Identified By Dense Coverage of the Complete Family of Nicotinic Receptor Subunit (CHRN) Genes
We analyzed 226 SNPs covering the complete family of 16 CHRN genes, which encode the nicotinic acetylcholine receptor (nAChR) subunits, in a sample of 1,050 nicotine-dependent cases and 879 non-dependent controls of…
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Self-Reported Sleep Habits in Middle School Girls: the Girls’ Middle School Longitudinal Sleep Survey
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Choline Acetyltransferase Expression During Spontaneous Sleep-Wake Bouts Over 24H
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Enhanced Alpha-Synuclein Expression in Human Neurodegenerative Diseases: Pathogenetic and Therapeutic Implications
Here we discuss the possibility that other mechanisms of alpha-synuclein elevation contribute to the pathogenesis of idiopathic, sporadic Parkinson's disease and other human synucleinopathies.
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Expression of Plasticity-Related Genes During Eszopiclone-Induced Sleep
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Nociceptin/Orphanin FQ Antagonists Ameliorate the Disease Pathogenesis During Inflammatory Bowel Disease
We evaluated the therapeutic potential of N/OFQ antagonists in C57Bl/6 mice in an IBD model after disease induction by treatment for 5 days with DSS, and subsequent observation of the…
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Therapeutic Efficacy of a Melatonin Agonist, Ramelteon, and a Benzodiazepine, Triazolam, in a Mouse Genetic Model of Advanced Sleep Phase Syndrome
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Pharmacokinetics and Immunogenicity Assays for a Human Monoclonal Antibody Mixture Specific for Botulinum Neurotoxin A
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Identification of “Sleep Genes” from Natural and Pharmacologically Induced Sleep Studies