Biomedical sciences publications

Abstract Background and purpose: Compounds that activate both NOP and μ-opioid receptors might be useful as analgesics and drug abuse medications. Studies were carried out to better understand the biological…

This volume examines conceptual, theoretical, and methodological considerations in the development of nicotine-dependence phenotypes and endophenotypes.

Presented is the neuroradiological signature of acute Wernicke's encephalopathy (WE), derived from different types of magnetic resonance imaging (MRI) sequences.

We hypothesized that the influence of opiates on sleep may be mediated, at least in part, by the ventrolateral preoptic nucleus (VLPO), a key cell group for producing behavioral sleep.

We used a global–local paradigm to assess component processes of visuospatial ability and MR diffusion tensor imaging (DTI) to examine whether alcoholism-related microstructural degradation of the corpus callosum contributes to…

We implemented a genetic model for population-based association studies with stratified samples and evaluated the impact on power with different genetic scenarios.

This mini-symposium review highlights some recent developments at the gene, molecular, cellular, and systems levels that have advanced this field.

Preliminary microarray analyses show that changes in behavioral state influence regional mRNA profiles; however, the impact of sleep on protein signatures is virtually unexplored. In these studies, cortical protein profiles…

The purpose of this study was to replicate these findings in an independent data set and more thoroughly investigate the role of genetic variation in the cluster of physically linked…