Artificial intelligence publications
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The MetaCyc Metabolic Pathway Database
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Using Transformations to Improve Semantic Matching
In this paper, we describe how transformations can augment existing semantic approaches to further improve matching.
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Execution Monitoring in Agent Teams
We characterize the domain-independent challenges posed by this problem, and describe how properties of domains influence the challenges and their solutions.
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HpyCyc: Helicobacter pylori Pathway/Genome Database
A Pathway/Genome Database for Helicobacter pylori is available at URL BioCyc.org. The database integrates the full genome of H. pylori with its computationally predicted metabolic pathways.
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A persistent web application for distribution of weather information in Scheme
A new tool is being used to generate lexical parsers in Scheme. It is based on a cascade of lexers, described by tagged regular expressions (TREs) written as s-expressions. In…
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PASSAT: A User-centric Planning Framework
We describe a plan-authoring system called PASSAT (Plan Authoring System based on Sketches, Advice, and Templates) that combines interactive tools for constructing plans with a suite of automated and mixed-initiative…
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Deductive Response to Geographic Queries
They may reside on different machines in diverse locations. Knowledge may be represented according to different frameworks, notations, or coordinate systems. The answer may not exist anywhere explicitly; it may…
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Reflections on Godel’s and Gandy’s Reflections on Turing’s Thesis
We sketch the historical and conceptual context of Turing’s analysis of algorithmic or mechanical computation and then discuss two responses to that analysis.
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Evaluation of computational metabolic-pathway predictions for Helicobacter pylori
We seek to determine the accuracy of computational methods for predicting metabolic pathways in sequenced genomes, and to understand the contributions of both the prediction algorithms, and the reference pathway…
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Conflict Management for Agent Guidance
This paper considers the problem of conflicting guidance for agents, making contributions in two areas: outlining a space of conflict types, and defining resolution methods that provide robust agent operation…
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The past, present and future of genome-wide re-annotation
We define the process of annotating a previously annotated genome sequence as 're-annotation', and examine the strengths and weaknesses of current manual and automatic genome-wide re-annotation approaches.
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The MetaCyc Database
MetaCyc is a metabolic-pathway database that describes 445 pathways and 1115 enzymes occurring in 158 organisms.