Biomedical sciences publications
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Who is to Blame if Snoring Becomes a Problem?
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Identification of Novel Cyp2A6*1B Variants: the Cyp2A6*1B Allele Is Associated with Faster in Vivo Nicotine Metabolism
We report evidence that CYP2A6*1B genotype is associated with faster nicotine clearance in vivo, which will be important to future CYP2A6 genotype association studies.
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Respiratory-Related Evoked Potentials During Sleep in Children
There have been no data on RREP during sleep in children. We thus examined children during sleep to determine whether early RREP components would be maintained during all sleep.
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AMP-Activated Protein Kinase Inhibits Transforming Growth Factor-Beta-Induced Smad3-Dependent Transcription and Myofibroblast Transdifferentiation
In wound healing, myofibroblast transdifferentiation (MFT) is a metaplastic change in phenotype producing profibrotic effector cells that secrete and remodel the extracellular matrix.
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Epigenetic Alteration of the Wnt Inhibitory Factor-1 Promoter Occurs Early in the Carcinogenesis of Barrett’s Esophagus
We hypothesized that downregulation of the Wnt inhibitory factor-1 (WIF-1) might be involved in the neoplastic progression of Barrett's esophagus (BE).
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Callosal Compromise Differentially Affects Conflict Processing and Attentional Allocation in Alcoholism, HIV, and Their Comorbidity
Diffusion tensor imaging was used to study the combined effects of HIV-infection and alcoholism (ALC) on corpus callosum (CC) integrity in relation to processes of attentional allocation and conflict resolution…
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Effects of Saporin-Induced Lesions of Three Arousal Populations on Daily Levels of Sleep and Wake
Here, we directly test this hypothesis by a simultaneous triple lesion of these neurons using three saporin-conjugated neurotoxins.
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Anti-Nociceptive and Anti-Allodynic Effects of a High Affinity NOP Hexapeptide [Ac-RY(3-Cl)YRWR-NH2] (Syn 1020) in Rodents
Syn 1020, a NOP receptor directed peptide, administered systemically has anti-nociceptive activity in both acute and chronic pain models in mice and rats respectively.
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SR 16435 [1-(1-(Bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin-2-one], a Novel Mixed Nociceptin/Orphanin FQ/μ-Opioid Receptor Partial Agonist: Analgesic and Rewarding Properties in Mice
We identified a novel nociceptin/orphanin FQ (NOP)/μ-opioid receptor agonist, SR 16435 [1-(1-(bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin-2-one], with high binding affinity and partial agonist activity at both receptors.
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Issues in Algorithm Characterization for Link Analysis
In this paper, we outline techniques for modeling algorithms that allow a system architecture to reason about their behavior and performance, individually and in combination.
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Advanced Patterns and Matches in Link Analysis
The Link Analysis Workbench (LAW) is a tool for detecting and monitoring situations of interest using inexact matching of graphical patterns.
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The comprehensive updated regulatory network of Escherichia coli K-12
One hundred and fifty new interactions have been added to our databases as a result of this specific curation effort, in addition to those added as a result of our…