Publications
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Optogenetic Manipulation of Activity and Temporally Controlled Cell-Specific Ablation Reveal a Role for MCH Neurons in Sleep/Wake Regulation
To determine the physiological role of MCH neurons, newly developed transgenic mouse strains that enable manipulation of the activity and fate of MCH neurons in vivo were generated using the…
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3D Imaging Reveals Electrodynamics of Polar Cap Aurora
Rishbeth prizewinners Hanna Dahlgren and colleagues investigate the nature of an auroral arc appearing within the deep polar cap region.
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Using the Idea Manager to Promote Coherent Understanding of Inquiry Investigations
This study examines the ideas students generated during an online inquiry investigation and how students used these ideas to construct scientific explanations about everyday phenomena.
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The Adaptor Protein SAP Regulates Type II NKT-Cell Development, Cytokine Production, and Cytotoxicity against Lymphoma
Here, using a type II NKT-cell TCR transgenic mouse model, we demonstrated that CD1d-expressing hematopoietic cells, but not thymic epithelial cells, meditate efficient selection of type II NKT cells.
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Coordinated Ionospheric Observations Indicating Coupling between Preonset Flow Bursts and Waves That Lead to Substorm Onset
A critical, long-standing problem in substorm research is identification of the sequence of events leading to substorm expansion phase onset.
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Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function
The sleep disorder narcolepsy results from loss of hypothalamic orexin/hypocretin neurons. Although narcolepsy onset is usually postpubertal, current mouse models involve loss of either orexin peptides or orexin neurons from…
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GABAB Agonism Promotes Sleep and Reduces Cataplexy in Murine Narcolepsy
We evaluated the effects of chronic administration of GHB and the GABA B agonist R -baclofen ( R -BAC) on arousal state and cataplexy in two models of narcolepsy: orexin/ataxin-3…
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A Novel Scheme for Speaker Recognition Using a Phonetically-Aware Deep Neural Network
We propose a novel framework for speaker recognition in which extraction of sufficient statistics for the state-of-the-art i-vector model is driven by a deep neural network (DNN) trained for automatic…
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ASR Error Detection Using Recurrent Neural Network Language Model and Complementary ASR
Our goal is to locate errors in an utterance so that the dialogue manager can pose appropriate clarification questions to the users.
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An Autoencoder with Bilingual Sparse Features for Improved Statistical Machine Translation
We propose a natural autoencoder that maps all the discrete and overlapping sparse features for each SCFG rule into a continuous vector, so that the information encoded in sparse feature…
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Computationally-Efficient Endpointing Features for Natural Spoken Interaction with Personal-Assistant Systems
We elicit personal-assistant speech using a recognizer with a dramatically increased endpoint threshold, and find frequent non-final pauses. Based on the new data, we develop low-cost acoustic features to discriminate…
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Dissociation of Preparatory Attention and Response Monitoring Maturation During Adolescence
The objective was to assess development of EEG markers of these strategies and their role in both preparatory attention (contingent negative variation, CNV) and response monitoring (Error Related Negativity, ERN,…