Publications
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Gene-Environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson’s Disease
Here we describe the use of a neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), which produces a nigrostriatal lesion to elucidate the distinct contributions of LOX isozymes to neurodegeneration related to PD.
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Non-Invasive Recognition of Poorly Resolved Integrated Circuit Elements
We present a non-invasive method for recognition of components in a digital CMOS integrated circuit (IC). We use a confocal infrared laser scanning optical microscope to collect multimodal images through…
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Design of a Serum Stability Tag for Bioactive Peptides
Here we explored a possibility of designing a serum stability tag made of natural amino acids. We observed that a diproline motif (-Pro-Pro-) shows remarkable stability against serum endopeptidases.
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Synthesis for Polynomial Lasso Programs
We present a method for the synthesis of polynomial lasso programs. These programs consist of a program stem, a set of transitions, and an exit condition, all in the form…
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Addition of Escherichia coli K–12 Growth-Observation and Gene Essentiality Data to the EcoCyc database
We have integrated data on the growth or nongrowth of E. coli K-12 obtained from published observations using a variety of individual media and from high-throughput phenotype microarrays into the EcoCyc database.
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Update on Mixed-Salt Technology Development for CO2 Capture from Post-Combustion Power Stations
The new mixed-salt technology combines the well-known ammonia and potassium carbonate technologies with improved reaction kinetics and reduced emissions.
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Large-Scale Analogical Reasoning
In this paper, relying on a well-curated biology KB, we present a specific implementation of comparison questions inspired by a general model of analogical reasoning.
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PortEco: A Resource for Exploring Bacterial Biology through High-Throughput Data and Analysis Tools
PortEco ( http://porteco.org) aims to collect, curate and provide data and analysis tools to support basic biological research in Escherichia coli.
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Comparative Molecular Field Analysis of Fenoterol Derivatives Interacting with an Agonist-Stabilized Form of the β(2)-Adrenergic Receptor
The β2-adrenergic receptor (β2-AR) agonist [3H]-(R,R′)-methoxyfenoterol was employed as the marker ligand in displacement studies measuring the binding affinities (Ki values) of the stereoisomers of a series of 4′-methoxyfenoterol analogs in…
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Vapor Pressure of Thiodiglycol
The new TDG vapor pressure data are in sharp contrast to widely accepted values from previous literature.
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Young Youth Explore Geospatial Data for Citizenship Project: A case study
Whether in formal or informal science youths’ engagement with data, particularly raw data, is threatened when supports are insufficient for drawing meaning from the data. For example, there may be…
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A Tailoring Algorithm to Optimize Behavior Change
A new algorithm, developed with data from smoking cessation clinical trials and published practice guidelines, is designed to predict the likelihood of abstinence.