Publications
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Non-Clinical Safety Evaluation of Xoma 3AB, a Novel Triple Antibody Drug Product Targeting Botulinum Toxin Type a, in Sprague-Dawley Rats
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Structure and Function of Parkin E3 Ubiquitin Ligase Reveals Aspects of RING and HECT Ligases
Here we present the 1.58 Å structure of Parkin-R0RBR, revealing the fold architecture for the four RING domains, and several unpredicted interfaces.
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Antileishmanial Activity of Natural Product-Like Naphthoquinones
The antileishmanial activity of compounds inspired by naphthoquinone secondary metabolites from Bignoniaceae is presented.
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Video Object Segmentation through Spatially Accurate and Temporally Dense Extraction of Primary Object Regions
In this paper, we propose a novel approach to extract primary object segments in videos in the ‘object proposal’ domain. The extracted primary object regions are then used to build…
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Designing Early Childhood Math Games: A Research-Driven Approach
This paper describes the iterative research and development process used by the Next Generation Preschool Math project, which integrates content analysis, logic model processes, and iterative design and research approaches.
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A New Perspective for Schizophrenia: TAAR1 Agonists Reveal Antipsychotic- and Antidepressant-Like Activity, Improve Cognition and Control Body Weight
We show that activation of the trace amine-associated receptor 1 (TAAR1), a modulator of monoaminergic neurotransmission, represents a novel therapeutic option.
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Multi-domain information fusion for insider threat detection
In this paper we report our effort on detecting malicious insiders from large amounts of work practice data.
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Interest flooding attack and countermeasures in Named Data Networking
In this paper we investigate effective solutions to mitigate Interest flooding.
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Random acts of kindness: the intelligent and context-aware future of reciprocal altruism and community collaboration
This paper highlights the possibilities for today's researchers and innovators to turbocharge community collaboration by developing the required technologies.
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FERN: a unifying framework for name resolution across heterogeneous architectures
We introduce FERN (Federated Extensible Resolution of Names), the first framework designed to enable efficient name resolution across heterogeneous name resolution systems operating in dynamic or static networks.
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Testing a novel parking system: on-street reservations
We developed a novel parking system that allows people to reserve on-street parking, meant to reduce congestion, increase convenience, and raise revenue.
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Echoes from the past: how technology mediated reflection improves well-being
We built Echo, a smartphone application for recording everyday experiences and reflecting on them later.