Publications
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Conceptual Models of Structure and Function
We report our achievements in creating conceptual, multidimensional models of biological structure and function out of the linear text of an introductory biology textbook.
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A General Approach to Online Sensor Calibration for Navigation Using Factor Graphs
We present a general method for online sensor calibration using factor graphs, which can be applied to a wide range of sensors and parameter types.
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A Mechanism of Rapidly Reversible Cerebral Ventricular Enlargement Independent of Tissue Atrophy
Here, multimodal imaging, incorporating structural MRI, MRS, and DWI, was used in rats exposed to binge ethanol to provide insight into a mechanism of reversible ventricular enlargement.
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Understanding the Sleep-Wake Cycle: Sleep, Insomnia, and the Orexin System
Andrew D. Krystal, MD, MS, gathered a panel of experts in the area of the sleep-wake cycle and insomnia to review recent research and advances in understanding, current treatments for…
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Cytotoxic Monacolin Analogs from Monascus Purpureus-Fermented Rice
Two new monacolin analogs, monacolins O (1) and P (2), along with three known analogs, have been isolated from the ethanolic extract of Monascus purpureus-fermented rice.
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Dead End Metabolites — Defining the Known Unknowns of the E. coli Metabolic Network
We have analysed the occurrence of dead end metabolites within the database – these are metabolites which lack the requisite reactions (either metabolic or transport) that would account for their…
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Algorithms for Geodesics
Algorithms for the computation of geodesics on an ellipsoid of revolution are given. These provide accurate, robust, and fast solutions to the direct and inverse geodesic problems and they allow…
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Updating and Curating Metabolic Pathways of TB
The overall goal of the TBCAP 2012 exercise was to gather and compile various data types and use this information with oversight from the scientific community to provide additional information…
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KB_Bio_101: A challenge for OWL Reasoners
We describe the axiomatic content of a biology knowledge base that poses both theoretical and empirical challenges for OWL reasoning.
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Discovery of Community Structures in a Heterogeneous Professional Online Network
We report a study of an international online network of educators involved in many forms of professional development and peer support, including sponsored and volunteer-driven activities taking place in both…
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KB_Bio_101: A Challenge for TPTP First-Order Reasoners
We describe the axiomatic content of a biology knowledge base that poses both theoretical and empirical challenges for knowledge intensive reasoning.
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Poker Flat Incoherent Scatter Radar Observations of Anomalous Electron Heating in the E Region
A comprehensive 2-year dataset collected with the Poker Flat Incoherent Scatter Radar (PFISR) located near Fairbanks, Alaska (MLAT = 65.4° N) is employed to identify and analyse 22 events of…