Publications
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Comparative Analysis of the Substrate Preferences of Two Post-Proline Cleaving Endopeptidases, Prolyl Oligopeptidase and Fibroblast Activation Protein Alpha
Post-proline cleaving peptidases are promising therapeutic targets for neurodegenerative diseases, psychiatric conditions, metabolic disorders, and many cancers.
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Cortical nNOS Neurons Co-Express the NK1 Receptor and are Depolarized by Substance P in Multiple Mammalian Species
To evaluate the degree of co-expression of nNOS and NK1 in the cortex among mammals, we used double immunofluorescence for nNOS and NK1 and determined the anatomical distribution in mouse,…
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Fyn Promotes Th17 Differentiation by Regulating the Kinetics of RORγt and Foxp3 Expression
In this study, we show evidence that the Src family tyrosine kinase Fyn helps regulate this Th17/TREG balance.
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Stereo Vision Embedded System for Augmented Reality
Stereo Vision processing is a critical component of Augmented Reality systems that rely on the precise depth map of a scene to properly place computer generated objects with real life…
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Anterograde Episodic Memory in Korsakoff Syndrome
In this review we highlight the historical studies that examined anterograde episodic memory processes in KS, present a timeline and evidence supporting the myriad theories proffered to account for this…
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A unified approach for audio characterization and its application to speaker recognition
Knowledge of the nuisance characteristics present in the signal can be used to improve performance of the system. In some cases, the nature of these nuisance characteristics is known a…
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The Stereoselective Sulfate Conjugation of 4′-Methoxyfenoterol Stereoisomers by Sulfotransferase Enzymes
The presystemic sulfate conjugation of the stereoisomers of 4′-methoxyfenoterol, (R,R′)-MF, (S,S′)-MF, (R,S′)-MF, and (S,R′)-MF, was investigated using commercially available human intestinal S9 fractions, a mixture of sulfotransferase (SULT) enzymes.
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Adaptive and Discriminative Modeling for Improved Mispronunciation Detection
In this work, we extend our approach with the use of model adaptation and discriminative modeling techniques, inspired on methods that have been effective in the area of speaker identification.
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Trace Amine-Associated Receptor 1 Partial Agonism Reveals Novel Paradigm for Neuropsychiatric Therapeutics
Here we report on the identification and characterization of the first selective and potent TAAR1 partial agonist.
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Effects of audio and ASR quality on cepstral and high-level speaker verification systems
We evaluate the effect that improved audio quality has for speaker verification performance, using a recently released full-bandwidth version of microphone data from the SRE2010 evaluation.
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Salience-Based Compression: Providing FMV Over Low-Bit Rate Channels
We introduce Salience-Based Compression (SBC), a vision-guided pre-filtering technology, coupled with standards-based video coding.
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Adaptive Smoothing in Real-Time Image Stabilization
This paper discusses several novel methods that have demonstrated on a real-time platform including an IIR filter, a single Kalman filter and an interactive multi-model filter.