Publications
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The Serine-Proline Turn: A Novel Hydrogen-Bonded Template for Designing Peptidomimetics
Factors that contribute to the formation of SP turns include controlling backbone flexibility and amino acid chirality along with creating a hydrophobic environment around the intramolecular hydrogen bonds.
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Accurate Atom-Mapping Computation for Biochemical Reactions
We introduce a new method for computing atom mappings called the minimum weighted edit-distance (MWED) metric.
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Carbohydrate Antigen Microarrays
This chapter describes one of my laboratory’s working protocols for carbohydrate-based microarrays.
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Metabolomics Reveals Amino Acids Contribute to Variation in Response to Simvastatin Treatment
We used a gas chromatography-time-of-flight mass-spectrometry-based metabolomics platform to evaluate global effects of simvastatin on intermediary metabolism.
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SRIUBC: simple similarity features for semantic textual similarity
We describe the systems submitted by SRI International and the University of the Basque Country for the Semantic Textual Similarity SemEval-2012 task.
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Towards Noise-Robust Speaker Recognition Using Probabilistic Linear Discriminant Analysis
This work addresses the problem of speaker verification where additive noise is present in the enrollment and testing utterances.
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AT-1001: A High Affinity and Selective alpha 3 beta 4 Nicotinic Acetylcholine Receptor Antagonist Blocks Nicotine Self-Administration in Rats
In order to better examine this receptor subtype, we have identified and characterized the first high affinity and selective α3β4 nAChR antagonist, AT-1001, both in vitro and in vivo.
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Learning by Demonstration for a Collaborative Planning Environment
We describe the deployment of a learning by demonstration capability to support user creation of automated procedures in a collaborative planning environment that is used widely by the U.S. Army.
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A Toolkit for the Design of Ambisonic Decoders
We discuss the issues involved and describe a set of tools for generating optimized decoder solutions for irregular loudspeaker arrays and demonstrate those tools with practical examples.
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Remapping the Brain to Compensate for Impairment in Recovering Alcoholics
We tested whether previously published functional magnetic resonance imaging data acquired in 15 recovering alcoholics and 15 controls at rest and while performing a spatial working memory task would fulfill…
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Association Between Daily Cigarette Consumption and Hypertension Moderated by CYP2A6 Genotypes in Chinese Male Current Smokers
The purpose of this study was to assess whether cytochrome P450 enzyme 2A6 (CYP2A6) genotypes moderate the association between smoking and hypertension.
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Transcriptional Regulation of Gene Expression During Osmotic Stress Responses by the Mammalian Target of Rapamycin
We have approached this question by analyzing the effect of mammalian target of rapamycin (mTOR), a central growth controller, on the osmotic stress response.