Publications
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Association of the Nicotine Metabolite Ratio and CHRNA5/CHRNA3 Polymorphisms with Smoking Rate Among Treatment-Seeking Smokers
Genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in the CHRNA5/A3/B4 gene cluster with heaviness of smoking.
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Thermal and Electrical Transport Properties of Spark Plasma-Sintered HfB2 and ZrB2 Ceramics
The thermal conductivity was found to decrease with increasing temperature for all materials. Results are discussed in terms of sample morphology and compared with data previously reported in the scientific…
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Direct inhibition of hypocretin/orexin neurons in the lateral hypothalamus by nociceptin/orphanin FQ blocks stress-induced analgesia in rats
We tested the hypothesis that N/OFQ modulates the SIA directly via the inhibition of the Hcrt neurons in the lateral hypothalamus.
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Sleep and the Brain
This issue’s special section on “Sleep through the Ages” contains papers addressing the neurological and neuropsychological implications of sleep in adolescents, older adults and insomnia sufferers, highlighting relations of sleep…
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Changes in Sleep as a Function of Adolescent Development
While changes in sleep across adolescence are a normal part of development, many adolescents are getting insufficient sleep and are consequently, less likely to perform well at school, more likely…
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Competition Between Intradomain and Interdomain Interactions: a Buried Salt Bridge Is Essential for Villin Headpiece Folding and Actin Binding
We used mutational analysis, monitored by CD and NMR, and functional assays to determine the role of this buried salt bridge.
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A Melanoma Molecular Disease Model
This paper describes such a Melanoma Molecular Disease Model reflecting the latest scientific, clinical, and technological advances.
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Summer Blooms of Diatom-Diazotroph Assemblages and Surface Chlorophyll in the North Pacific Gyre: a Disconnect
We compared diatom-diazotroph assemblage abundance to size-fractionated chlorophyll and satellite ocean color chlorophyll estimates to evaluate how DDAs affected ocean color estimates in the eastern and central North Pacific gyre…
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Disruption of Functional Connectivity of the Default-Mode Network in Alcoholism
We examined DMN functional connectivity using functional magnetic resonance imaging (fMRI) data and graph theory analysis.
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Phase 0 Clinical Chemoprevention Trial of the Akt Inhibitor Sr13668
We designed and conducted the first-ever phase 0 chemoprevention trial to evaluate and compare the effects of food and formulation on SR13668 bioavailability.
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Application of System of Rice Intensification Practices in the Arid Environment of the Timbuktu Region in Mali
Small-scale, village-based irrigation schemes, usually 30–35 ha in size, irrigated by a diesel motor pump, have become important to improve food security in this arid region.
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Using Large-Scale Databases in Evaluation: Advances, Opportunities, and Challenges
The authors illustrate both the opportunities provided by higher quality, interoperable data systems and the challenges encountered when using databases to identify issues of concern, test the plausibility of a…