Publications
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Discovery of 1-[3-(4-Bromo-2-Methyl-2H-Pyrazol-3-Yl)-4-Methoxyphenyl]-3-(2, 4-Difluorophenyl)Urea (Nelotanserin) and Related 5-Hydroxytryptamine 2A Inverse Agonists for the Treatment of Insomnia
We describe here a series of 5-HT2A inverse-agonists that when dosed in rats, both consolidate the stages of NREM sleep, resulting in fewer awakenings, and increase a physiological measure of sleep…
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Refractive Index Measurements of Ammonia and Hydrocarbon Ices at 632.8 nm
Optical constants in a broad temperature and wavelength range are important input parameters in radiative transfer models used in studies of planetary atmospheres.
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The Alignment of the Informal and Formal Organizational Supports for Reform: Implications for Improving Teaching in Schools
This article combines social network analysis with interview data to analyze how well the formal and informal aspects of a school’s social context are aligned.
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Soccer science and the Bayes community: exploring the cognitive implications of modern scientific communication
This paper reports on a series of experiments in this area, and a prototype implementation using a research platform called CACHE.
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Handheld, microfluidic-based detection platform for on-the-flow analyte characterization
We have demonstrated a new optical detection technique that delivers high signal-to-noise discrimination without precision optics to enable a flow cytometer that can combine high performance, robustness, compactness, low cost,…
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Microfluidic-based detection platform for on-the-flow analyte characterization
In this paper we will describe and illustrate a new detection technique that will enable a compact, microfluidic-based flow cytometer that satisfies POC specifications for performance, robustness, compactness, cost, reagent…
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Lasing of semi-polar InGaN/GaN(1122) heterostructures grown on m-plane sapphire substrates
Results for long-wavelength emitters are presented for semi-polar InGaN/AlGaN/GaN heterostructures grown on GaN(1122)/m-sapphire templates by metalorganic chemical vapor deposition.
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Compact and fast read-out for wavelength-encoded biosensors
We will describe a compact and fast wavelength monitor that can resolve sub-pm wavelength changes.
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Learning to Ask the Right Questions
Asking questions can clarify concepts, test hypotheses, add missing information, or provide additional knowledge to facilitate learning. The last item motivates the work described in this paper.
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Lysosomal Degradation of Alpha-Synuclein in Vivo
In this study, lysosomal clearance of α-synuclein in vivo was indicated by the detection of α-synuclein in the lumen of lysosomes isolated from the mouse midbrain.
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Mendel: Efficiently Verifying the Lineage of Data Modified in Multiple Trust Domains
We describe Mendel, a protocol with a three-pronged strategy that combines eager signature verification, lazy trust establishment, and cryptographic ordering witnesses to yield fast lineage verification in distributed multi-domain environments.
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Student Modeling In An Intelligent Tutoring System.
In this chapter we review and summarize some of the main studies we have done with the system. Our results are surprising- by providing tutoring to students while they are…