Publications
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mRNA Splicing-Modulatory Pharmacophores: The Total Synthesis of Herboxidiene, a Pladienolide-Herboxidiene Hybrid Analog and Related Derivatives
We report an improved enantioselective synthesis of herboxidiene and the first report of its biologically active totally synthetic analog: 6-norherboxidiene.
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Distributed Coverage with Mobile Robots on a Graph: Locational Optimization and Equal-Mass Partitioning
This paper presents decentralized algorithms for coverage with mobile robots on a graph. We use distributed vertex substitution for locational optimization and equal mass partitioning, and the controllers minimize the…
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Automatic 3D Change Detection for Glaucoma Diagnosis
We propose an automatic approach for detecting these changes in 3D models reconstructed from fundus images of the same patient taken at different times.
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Tracking Elevated Pollution Layers with a Newly Developed Hyperspectral Sun/Sky Spectrometer (4STAR): Results from the TCAP 2012 and 2013 Campaigns
We compare results with coincident measurements. We find 0.045 g/cm2 (4.2%) negative bias and 0.28 g/cm2 (26.3%) root-mean-square difference (RMSD) in water vapor layer comparison with an in situ hygrometer and an overall RMSD…
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Influence of Systemic Interleukin-6 on the Inverse Association between Your-Choice American Heart Diet and a 41-Year Mortality Risk from Coronary Heart Disease among Men
Our premise is systemic inflammation measured as plasma interleukin-6 levels medicates the association between whole diet and long-term mortality risk from coronary heart disease independent of genes.
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Simulations for STEM Learning: A Systematic Review and Meta-Analysis (Brief)
This review addresses a gap in the current research literature on computer-based simulations for STEM learning.
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Heater-Induced Ionization Inferred from Spectrometric Airglow Measurements
Spectrographic airglow measurements were made during an ionospheric modification experiment at High Frequency Active Auroral Research Program on 12 March 2013.
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Simulations for STEM Learning: Systematic Review and Meta-Analysis (Executive Summary)
This executive summary presents an overview of the process and initial findings of a systematic review and meta-analysis of the literature on computer simulations for K–12 science, technology, engineering, and…
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Addition of Escherichia coli K-12 Growth Observation and Gene Essentiality Data to the Ecocyc Database
We have integrated data on the growth or nongrowth of E. coli K-12 obtained from published observations using a variety of individual media and from high-throughput phenotype microarrays into the…
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The Learning Registry: Applying Social Metadata for Learning Resource Recommendations
The Learning Registry makes it possible for disparate sources to publish learning resource social/attention metadata—data about users of and activity around resources.
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Simulations for STEM Learning: Systematic Review and Meta-Analysis (Full Report)
This report presents an overview of the process and initial findings of a systematic review and meta-analysis of the literature on computer simulations for K–12 science, technology, engineering, and mathematics…
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Learning Online: What Research Tells Us About Whether, When and How
The book describes available research about how best to implement different forms of online learning for specific kinds of students, subject areas, and contexts.